Soon after arriving in the English capital, the Williams sisters and their United States team mates got a taste of Olympic traffic gridlock, delaying their pre-Games news conference.
Everyone then had a good chuckle at the expense of doubles partners and brothers Bob and Mike Bryan, who were denied entry into the Olympic media centre for not having validated credentials.
Serena, still basking in the glow of her fifth Wimbledon singles title, quickly made it clear, however, that she was not back in London for a few laughs, but for medals.
If the 14-times Grand Slam winner can claim the women's gold she would become the only player to win all four slams, plus singles and doubles gold.
"It's exciting to be back so soon, usually we have to wait 12 months to walk back on to centre court," Serena, who will set up camp with her sister and the rest of the U.S. tennis team at a hotel near Wimbledon, told the news conference.
"For me, I'm going to be really excited to have such a quick turn-around and get back on the grass where I love to play."
Since rejoining the Summer Games programme in 1988 after a 64-year absence, tennis and the Olympics have not always been a comfortable fit, with many players putting a grand slam victory ahead of a gold medal.
Wimbledon and the Olympics, two ancient sporting institutions, will come together, however, at the All England Club.
"Growing up as tennis players you always dream of winning grand slams and doing well at tournaments like Wimbledon," said Venus, who will defend the doubles title with her sister.
"To have an opportunity to win a gold medal and be mentioned among all the great athletes, that's an honour."
Between them, Serena and Venus have won 10 singles titles on Wimbledon's manicured lawns along with five doubles crowns, the most recent three weeks ago.
They have never lost as a doubles partnership at an Olympic Games, taking gold in 2000 and 2008, while Venus also has a singles gold in her trophy case from Sydney.
There is also the possibility of a Williams playing mixed doubles and adding to their medal haul. The U.S. will not confirm their mixed doubles teams until next Tuesday.
After pulling out of her World Team Tennis commitments to rest a sore back last week, Serena had more bad news for her opponents, saying she was back to full fitness.
"I think when we first heard about mixed that we wanted to play for all three and knew we would really have to be at the ultimate fitness level to do so," said Venus. "But at the end of the day it's going to be what our team captains want.
"Obviously we're interested in seeing who could have the best chance to win because we really want to bring medals home.
"It's about the betterment of the team and what would be the best for the USA."