Sharapova, who spoke optimistically about the new season on Monday, was forced to withdraw from her second-round match against Australia's Jarmila Gajdosova in Brisbane, saying it was the "smart move" to make.
The French Open champion also pulled out of an exhibition match against Caroline Wozniacki at the end of December in Seoul because of a sore collarbone.
"That's why I had to pull out of the exhibition match I had in Korea," she said at a news conference on Tuesday.
"I had a bit of inflammation in my collarbone. My doctor in New York told me I couldn't really do much overhead training for about a week.
"So to be fair, I haven't really given myself a chance to pretty much hit any serves or anything over my head. Just been practicing groundstrokes.
"So I just kind of ran out of time here."
While the season's first Grand Slam set to start on January 14, Sharapova was not overly concerned about her preparations.
"I still have quite a bit of time to prepare for the Australian Open," she added. "I'm on the right track, been training really well, so I just don't want to jeopardise what I've gained in the off-season so far.
"I just have to make a smart move here."
Sharapova said she expected to travel straight to Melbourne rather than make a late entry into the Sydney International next week.
"I have my own fair share of experience, and know that it's much more important to be healthy to go into a big tournament like the Australian Open than to go into something big with a lot of matches and feel like you're not prepared health-wise," she said.
"You never know with these things. I mean, there are so many parts of the body where I'm sure if every one of us did an examination we would find a lot things wrong with us.
"But when it started getting a little too painful, I had to do a few tests. The doctor said, 'You always want to train but it's the off-season. He said I just had to calm it down for like five days.
"When I started back here I was feeling much better, but just like I said, couldn't do much overhead stuff and ran out of time."
Brisbane tournament director Cameron Pearson said Sharapova had made every effort to play.
"We feel for Maria because we saw first-hand how badly she wanted to play for the people of Brisbane," he said.
"She has been fantastic since she got here and worked hard in the gym, on court and in the medical room to do everything she could to get herself right.
"Unfortunately she didn't make it. We hope that she can recover sufficiently from the injury to take the court for the Australian Open and wish her all the best for the summer."
At the tournament the upsets kept on coming, with Petra Kvitova and Sara Errrani the latest high-profile players to be bounced out.
Sixth seed Kvitova was humbled by Anastasia Pavlyuchenkova, who won through 6-4 7-5 in a solid performance.
"Everything was really tough last year, but I think I got a lot of experience through it all, and recognized I had a lot of things to work on," Pavyluchenkova said. "I worked on everything in the off-season - my serve got much better, my movement, just a lot of physical and mental things. But I'm not going to say it's all perfect now. I still have a lot to improve. Of course it's nice to see it's already paying off a little bit."
Errani crashed out 4-6 6-1 7-5 to Daniela Hantuchova in a two-hour 25-minute epic.
But there were no such dramas for the third seed Serena Williams, who needed an hour to dispatch Alize Cornet 6-2 6-2 in the evening match.