Jones, who also has six British and Irish Lions caps, has been level on 100 Wales appearances with former back Gareth Thomas since playing against the Barbarians in June, as a calf injury has kept him on the sidelines.
The 33-year-old, who made his debut 13 years ago, will appear in his fourth World Cup having finally shaken off the problem that first flared up during the warm-up for August's Twickenham match against England.
"From my point of view, it's great to see a player who will be winning his 101st cap who is a little bit edgy, a bit nervous, going into this game knowing how important his performance is," said coach Warren Gatland.
Wales will expect an easy victory against the African side who have lost all 14 World Cup games they have played, most recently going down 87-0 to South Africa last week.
The Welsh, who lost by a point to the Springboks in their opening match, then turn their attention to their final game against Fiji, when another win would probably be enough to send them into the quarter-finals.
Wales: 15-Lee Byrne, 14-Leigh Halfpenny, 13-Jonathan Davies, 12-Scott Williams, 11-Aled Brew, 10-Stephen Jones, 9-Tavis Knoyle, 8-Toby Faletau, 7-Sam Warburton (Captain), 6-Ryan Jones, 5-Alun Wyn Jones, 4-Bradley Davies, 3-Craig Mitchell, 2-Lloyd Burns, 1-Gethin Jenkins. /// Replacements: 16-Ken Owens, 17-Ryan Bevington, 18-Luke Charteris, 19-Andy Powell, 20-Lloyd Williams, 21-Rhys Priestland, 22-George North.
Namibia: 15-Chrysander Botha, 14-Danie van Wyk, 13-Piet van Zyl, 12-Darryl de la Harpe, 11-Danie Dames, 10-Theuns Kotze, 9-Eugene Jantjies, 8-Jacques Nieuwenhuis, 7-Jacques Burger (captain), 6-Tinus du Plessis, 5-Nico Esterhuyse, 4-Heinz Koll, 3-Jane du Toit, 2-Hugo Horn, 1-Johnnie Redelinghuys. /// Replacements: 16-Bertus O'Callaghan, 17-Raoul Larson, 18-Wacca Kazombiaze, 19-Rohan Kitshoff, 20-Ryan de la Harpe, 21-TC Losper, 22-David Philander.