Wales also host Samoa on November 16, New Zealand on November 24 and Australia on December 1.
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Argentina see out the win - plenty of errors and a lack of invention from Wales on an admittedly unsteady surface in Cardiff.
Another disappointing phase from Wales there - and the Argentina maul now preserves the ball with a minute left on the clock.
Argentina hold Wales at bay a metre from the tryline on the right. Penalty taken quickly in the middle with the tap but the options out wide are ignored by McCusker and play is halted as he holds the ball on the ground. Argentina kick the set-piece to touch.
North just keeps the ball alive as he is ushered into touch. Bevington then Turnbull on the other side of the pitch gain ground then play moves back to the left again.
Argentina a wall of bodies near halfway, repelling the Wales attacks.
And doesn't. Halfpenny catches and brings the ball out.
They win the scrum and another penalty follows. Sanchez will try his luck from there, but he won't reach the posts from here on this slippy turf.
Argentina have a scrum on halfway as the short kick-off is collected by Wales - but the ref deems that it did not go 10 metres.
ARGENTINA PENALTY - 12-26: He clips it through cleanly! Great kick! Long way back from here for Wales.
Changes abound from both sides as Argentina have a penalty on the left. Sanchez over it with blood dripping from his chin.
Sanchez with another drop-goal attempt, but the pass was low and he couldn't set himself properly.
Williams to Halfpenny, who tries to go low past Camacho but slips again as he changes direction.
Williams now tackled on the right but picks up a penalty. They will surely kick to the corner - a penalty won't get them within a score.
Wales respond to Argentina's period of dominance, running the ball to cries of desperation from the stands.
England are running Fiji ragged.
CONVERSION ARGENTINA - 12-23: And Wales are in more trouble as Sanchez kicks a superb conversion from the right touchline.
TRY ARGENTINA - 12-21: Camacho finishes in the corner with a brilliant dive - confirmed by the video ref - after an offload by Imhoff.
Imhoff on the left about to be taken into touch and he plays a skilful sidefooted kick over a Wales head down the line... Cuthbert just there to carry into touch and save Wales.
Imhoff breaks and Argentina move the ball cleverly with quick hands but just lose the ball just as Wales were creaking.
Wales making a change: regular scrum-half Mike Phillips is on for Knoyle.
CONVERSION ARGENTINA - 12-16: Sanchez with a simple kick for a four-point lead.
TRY ARGENTINA - 12-14: Juan Manuel Leguizamon breaks the line and gets a hand free to offload to Lobbe as he is tackled. Lobbe then repeats the trick to find the supporting Imhoff... and he is free to cross under the posts!
Halfpenny runs from deep following a reverse pass from Priestland but slips again as he looks to break the Argentina line. Argentina have the scrum.
DROP-GOAL ARGENTINA - 12-9: Sanchez kicks his second drop-goal of the afternoon to draw Argentina closer to Wales again.
Argentina plugging away in enemy territory.
Wales penalised for going off their feet again but the set-piece is in the Argentina half.
Priestland with a bit of a sliced clearance from underneath his posts but finds touch with it.
WALES PENALTY - 12-6: The full-back sends it through for a six-point lead. Still a single-score lead though.
Halfpenny will have a chance to kick Wales further ahead with a penalty.
Wales now have a lineout in the Argentina half despite a couple of players slipping over while taking the ball into the tackle. Whenever I visit this ground the turf looks unstable and prone to ripping up.
Sanchez slips on the turf as he kicks and Priestland is given the ball to boot away. Argentina back with the ball in their own half.
Wales off their feet and Argentina have another penalty, this one on the right on the Wales 22.
Sanchez sends it towards the far post... and it comes back off it! Faletau dives on the rebound.
Penalty to Argentina from a central position.
Argentina kick us off and turn the ball over soon after.
The players are back out. Wyn-Jones is no more - at least in terms of this game - with that hand injury. Rob McCusker is on in his place.
Not as entertaining as I was hoping. Wales have only had 45% of possession but 63% of the territory... what should they do differently to see more attacking ball and get a stranglehold on this game?
Half-time in Cardiff, with Wales leading 9-6.
Wyn-Jones is now hurt.
Away scrum-half Martin Landajo attacks after Hernandez rips the ball out of Wyn-Jones's grasp. He rounds Toby Faletau, but the Wales No.8 recovers to tackle. Sanchez on the right delivers to Senatore and they take the ball left again, with Tuculet carrying a few metres from the tryline... Juan Martin Fernandez Lobbe mis-handles though and Wales hack clear.
Scrum-half Tavis Knoyle takes the dropping ball in the middle of a dozen players cleanly.
Wales win their lineout and drive down the middle through Josh Turnbull. Cuthbert finds a gap to gain a few metres but someone comes in from the side in the ruck and the penalty is Argentina's.
Argentina fail to release the ball in the ruck and Priestland will kick the set-piece clear... he sends it 60m down the field and bouncing into touch! Near the corner.
Halfpenny with a superb take under pressure at the birth of a Wales attack which ends with North being tackled at the other end of the pitch. Almost through down the touchline.
No yellow card for him - he said sorry immediately but he has all the time in the world to pull out of that, the second row.
Halfpenny with a very high up-and-under which does not gain much distance. Argentina do not deal with it and Wales have it back... the ball is sent deep into away territory but Hernandez takes it and clears to touch. And he is caught late and high by Alun Wyn Jones!
Tight-head prop Aaron Jarvis now hurt and receiving treatment after Argentina moved the ball infield and Wales won a scrum.
North now has a knock, holding some ice to his hip with the ball dead but continuing on.
Argentina win a lineout in Wales territory.
PENALTY WALES - 9-6: Wales take the lead for the first time as Halfpenny kicks from a central position. The fans getting louder.
Wales awarded a penalty outside the Argentina 22.
Roberts will not continue. Both sides losing their inside centres. And a fan in the front row takes the ball superbly as it is booted into the stands!
He leaves the fray, for now at least, and his replacement is not bad - James Hook.
Replacement Tuculet fumbles a Halfpenny clearance but the ball goes backwards. Jamie Roberts smashed by Tiesi as Argentina run with the ball and will receive treatment.
Cuthbert fed by Williams on the right but Camacho is solid in the tackle.
Argentina scrum as they seek to build more pressure. Wales star Halfpenny catches cleanly and whacks clear when the ball is sent deep to him.
Another long drop-goal attempt from Sanchez, this one sailing just wide from 40 metres.
Argentina turn the ball over again through Leonardo Senatore and there is a gap on the left for them to attack... Juan Imhoff rampages down the touchline and sends the grubber kick towards the tryline before he is tackled... Tiesi picks up but Priestland gets a tap tackle on him and the scrum goes to Wales for a knock-on. Lucky escape.
Up-and-under from Sanchez which Wales left wing George North cleans up under pressure.
Running rugby from deep from Wales led by Cuthbert. Wales then work the ball across the field to the left with men over, but their passing is too slow and the away side cover. Argentina scrum near halfway.
PENALTY WALES - 6-6: Halfpenny sends it through the posts from wide on the right to level.
He went over awkwardly on his right leg, bending the knee at an unnatural angle under the weight of wing Alex Cuthbert. The Argentina star leaves on a stretcher. Joaquin Tuculet replaces him.
Contepomi is hurt in that ruck.
Wales with the ball, attacking down the right. Argentina turn it over but the ref awards a penalty to the home side.
DROP-GOAL ARGENTINA - 3-6: Sanchez back in the pocket and strikes it well, straight down the middle to retake the lead for Argentina.
Full-back Juan Martin Hernandez with a grubber kick down the left with No.6 Leonardo Senatore chasing, but easily defended by Wales. Before that No.10 Sanchez also tried a low kick, which was blocked and came straight back to him.
Argentina have men over but the forwards take the ball towards the Wales 22. The hosts hold firm for now.
PENALTY WALES - 3-3: Leigh Halfpenny makes no mistake with a simple penalty from near the 22.
Aaron Jarvis leads the attack for the home side and wins a penalty.
The roof is closed, negating the effect of wind, but there is a sombre atmosphere inside the stadium.
PENALTY ARGENTINA - 0-3: Felipe Contepomi kicks the first points of the afternoon.
Penalty to Argentina as Ian Evans is penalised for a high tackle on Nicolas Sanchez.
Outside centre Scott Williams with a big hit as Argentina counterpart Gonzalo Tiesi carries over halfway.
Wales No.10 Rhys Priestland sends the ball deep into the Argentina half.
So this should be an entertaining and close game - who will win? /// Raymond (below): "If the welsh pack can even get parity with the argies they certainly have it behind the scrum to do damage. Argies very limited in the backline."
Wales, led by interim coach Rob Howley as Warren Gatland concentrates on his duties as British and Ireland Lions coach, belt out Land of My Fathers.
Time for the national anthems.
The teams are coming out under the floodlights.
Flanker Josh Turnbull makes his second start in place of the stricken Dan Lydiate and in the fourth and final change from the Grand Slam-winning side in March, Scott Williams takes the place of Jonathan Davies at centre. Fellow centre Jamie Roberts missed June's tour of Australia after knee surgery but returns as one of seven changes from the last test defeat in Sydney.
Ospreys prop Aaron Jarvis wins his first Wales cap in this opening November international scrum-half Mike Phillips has been dropped to the bench. Tavis Knoyle comes in for Phillips, who was suspended by his club Bayonne for off-pitch misdemeanours, and Jarvis will replace the injured Adam Jones in Cardiff.
Welcome to live coverage as Wales host Argentina in a Test match at the Millennium Stadium in Cardiff.