Exeter boss Rob Baxter believes his player are in the mood to make a final push towards achieving Heineken Cup qualification on Sunday.
Leicester are the most successful club in English rugby union history when it comes to winning league titles - but hooker Tom Youngs believes it is "too long"
Brian O'Driscoll starts in perhaps his final Six Nations match against Italy while Jonathan Sexton is out with a new injury.
Openside flanker Simone Favaro has returned to the starting line-up in one of three changes for Italy's final Six Nations championship match against Ireland.
Worcester recorded their first win since Christmas while Bath edged a bad-tempered thriller at The Rec.
Wasps' transformation from Aviva Premiership relegation candidates to title play-off challengers could be underlined at Worcester on Friday night.
Leicester prop Martin Castrogiovanni will captain Italy in their Six Nations championship match against Wales at the Stadio Olimpico.
Wasps maintained their unbeaten home record in the Aviva Premiership with a 33-29 victory over Gloucester.
Wasps captain Hugo Southwell has billed Sunday's Aviva Premiership clash against Gloucester as a "massive" game for both clubs.
Scotland ran riot as they thrashed Italy 34-10 in a magnificent Six Nations win at Murrayfield.
Gonzalo Canale will replace injured Alberto Sgarbi in the only change to Italy's side for the Six Nations match in Scotland.
South Africa-born Tobias Botes will start at scrum half as part of three changes for Italy's Six Nations opener against France on Sunday.
Former captain Thierry Dusautoir will make his return when France face Italy in Rome in their Six Nations opener on Sunday.
Tom Varndell scored the fastest hat-trick in Amlin Challenge Cup history as Wasps qualified for the quarter-finals.
Tom Varndell responded to his England omission with the fastest hat-trick in Amlin Challenge Cup history as Wasps qualified for the quarter
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