Beau Champion has been pulled from the clash as he recovers from an ankle complaint suffered in last round's win over Penrith.
He has been replaced in the centres by Steve Michaels, who will celebrate his 100th game.
Coach John Cartwright has Phil Graham on standby for William Zillman after the fullback left Thursday's training session with a back-hamstring complaint.
And forward Matt White is not expected to make the trip south after he spent the last two days in hospital battling a tonsilitis infection.
"It's a bit of a dog's brekky at the moment. We will do what we have to when the time comes," Cartwright said of naming a final 17.
Both the Titans (10th) and Dragons (11th) are on 14 points outside the top eight but the Gold Coast is one of the NRL's form sides after winning four of their last five games.