The only Australian male golfer to win a major in the past 16 years has missed the cut at the past four Opens.
The Victorian felt his game was coming together before Thursday's opening round after a nagging shoulder injury hindered his progress since finishing fourth at the US Masters in April.
"It is a shame, it was coming around really well by Masters time and I played quite well at the Masters and then the shoulder kind of got in the way," he said.
"I have played the last four weeks but still trying to find my feet I guess.
"I kind of felt I have played pretty well the last couple of weeks but not got much out of it.
"It is coming, golf is a bit of a mysterious game.
"There is no reason physically why I should not be able to play well."
It is the first time since 2003 that Royal St George's has hosted the tournament and Ogilvy is one of a dozen Australians in this year's field.
The course is located just outside of Sandwich, on England's south-eastern coastline in Kent.
It was the venue for Greg Norman's second major in 1993, the last time an Australian lifted the Claret Jug.
"It is a tough golf course but it is very doable if you play good shots but if you start going wrong ...," Ogilvy said.
"It has got a feel like a course that the good players will be on the leaderboard, where the cream will rise to the top by the end."
Ogilvy, who finished fifth and 16th at the Open in 2005 and 2006, said his ball striking had let him down in recent years.
"Just one of those things, it is disappointing my form in the past two years of this tournament," he said.
"But it is a ball striking test more than a putting test normally.
"I probably have not come here hitting the ball pretty well the past few years.
"I had a bit of a funky draw at (Royal) Birkdale but last year everyone got an odd draw (at St Andrew's).
"I did not feel like I played that bad.
"I wish I could have done better the past few years and hopefully after a few bad years, I can have a few good years."