The Circuit of the Americas race is scheduled for the weekend of November 17 next year following confirmation of the schedule by the FIA World Motor Sport Council yesterday.
The University of Texas football team is scheduled to play against Oklahoma State on November 16, in a event that is expected to draw a crowd of over 100,000 fans.
Both the university and the circuit chiefs have admitted the situation is far from ideal, with COTA eager to get a new date for the grand prix.
"Circuit of the Americas has expressed our strong preference for an alternate race date in 2013," chairman Bobby Epstein told the American-Statesman.
"We understand that setting a global calendar can be very challenging, involves many factors and is out of our control. We feel confident that Formula 1 has taken our concerns seriously and is working earnestly towards a collective solution.
"Ultimately, our 2013 race date may remain as it currently stands."
The Austin circuit made its debut on the Formula 1 calendar this year.