Sochaux, who unexpectedly finished fifth last season, are last in the standings with 21 points from 26 games, five points short of 17th placed Nancy.
"Something needed to be done and so FC Sochaux have decided to make a change. Mecha Bazdarevic is no longer the team's coach", the club said on their website.
Reserve team coach Eric Hely will replace Bazdarevic in a caretaker role.
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