Daniele De Rossi is out of the game at Napoli after Roma's appeal against his ban for punching Inter Milan's Mauro Icardi was rejected.
Italy coach Cesare Prandelli said playing Spain in a friendly three months before the World Cup may not be the best idea.
Roma are set to appeal the decision to ban Daniele De Rossi for three matches.
Roma’s Daniele De Rossi has been handed a three-match ban by Serie A’s disciplinary body after punching Mauro Icardi in the face.
AS Roma midfielder Daniele De Rossi and Inter Milan defender Juan Jesus were banned for three games on Monday for punching opponents during Saturday's goalless
Daniele De Rossi was left out of Italy's squad for the friendly against Spain after punching Mauro Icardi in a league match.
AS Roma missed the opportunity to close the gap on leaders Juventus as they were held to a goalless draw by Inter Milan.
Daniele De Rossi has admitted that before he was a player, he only followed Roma.
Alessandro Diamanti is impressed with his first match for Guangzhou Evergrande and confident he won’t miss out on an Italy call.
Roma missed a huge chance to gain ground on Juventus as they could only manage a 0-0 draw against Lazio at Stadio Olimpico.
AS Roma, with Gervinho in inspirational form, go into Sunday's Rome derby (1400 GMT) looking for more than local bragging rights as they face a crucial week
Two goals from in-form Gervinho gave AS Roma a thrilling 3-2 victory in their Italian Cup semi-final first leg against Napoli.
Unsettled defender Nicolas Burdisso could start for AS Roma in their Serie A clash with struggling Livorno on Saturday (1800 GMT), manager Rudi Garcia said.
Rudi Garcia hailed Radja Nainggolan for settling quickly into the Roma squad after their 4-0 victory over Genoa.
Juventus handed nine-man Roma their first defeat of the season in a 3-0 victory in Turin to edge closer to retaining their title.
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