Cycling has long battled a major doping problem, with a raft of top riders failing drugs tests and seven-times Tour champion Lance Armstrong being charged by the United States Anti-Doping Agency last month.
After a foul-mouthed insult aimed at the band of tweeters, Wiggins told a news conference: "I can't be doing with people like that.
“I say they’re just f****** w******. I cannot be doing with people like that. It justifies their own bone-idleness because they can’t ever imagine applying themselves to do anything in their lives.
“It’s easy for them to sit under a pseudonym on Twitter and write that sort of s***, rather than get off their a***s in their own lives and apply themselves and work hard at something and achieve something. And that’s ultimately it. C***.”
"It justifies their own bone idleness because they can't ever imagine applying themselves to anything in their lives."
He then stood up, said "cut" and received a round of applause from the media room, while riders and team mangers from across the sport later supported his outburst on Twitter, with Chris Froome saying, "Critics need to wake up and realise that cycling has evolved. Dedication and sacrifice = results. End of story!"
Wiggins, who holds a 10-second lead over defending champion Cadel Evans after nine days of the three-week race, also had a dig at tennis with millions more watching compatriot Andy Murray in the Wimbledon men's final than the Tour.
"Tennis is nothing. It only lasts one and a half hours," he barked.