Defending champion Ryder Hesjedal dropped out of the top 10 after losing more than a minute to his rivals on stage nine of the Giro, won by Maxim Belkov.
Britain's Bradley Wiggins lost precious seconds to his main rivals in stage four of the Giro d'Italia, won by Enrico Battaglin.
Bradley Wiggins crashed in the hilly Abruzzo region as Adam Hansen soloed to victory in stage seven of the Giro d'Italia.
German youngster John Degenkolb proved the strongest in a splintered finish in Matera depite a crash by his last Argos-Shimano lead-out man.
Javi Moreno bagged the 11th victory of the season for his Movistar team after triumphing in the Vuelta a Madrid.
Mark Cavendish won the opening stage of the Giro d'Italia in Naples to take the first maglia rosa of the race's 96th edition.
Roman Kreuziger upset the favourites with a remarkable solo win in the Amstel Gold Race in glorious sunshine at Valkenburg.
Euskaltel-Euskadi made it two wins from two at the Vuelta a Castilla y Leon as Juanjo Lobato won stage two.
Pablo Urtasun of Euskaltel-Euskadi won the opening stage of the Vuelta a Castilla y Leon in Valladolid.
European track cycling champion Valery Kaikov has been fired by the Rusvelo team for failing a drugs test.
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