Sciandri, who won Olympic bronze for Britain at the 1996 Olympics and recorded stage victories at the Tour de France and Giro d'Italia, will focus on developing the team's younger riders and identifying future talent.
The 43-year-old had been head coach at the British Cycling Academy in Italy as well as working with Team Sky.
Sciandri said the opportunity to work with BMC president Jim Ochowicz was a big factor.
"I spent three years with Jim when I was riding with Motorola," Sciandri said.
"He's clear, honest, correct and professional. Cycling needs a few more people like him to get things sorted out."
Sciandri joins Fabio Baldato, Michael Sayers and Rik Verbrugghe in BMC's staff of assistant directors.
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