AFPThe HTC-Highroad rider saw off the challenges of several other favourites to win the race in northern Italy, the first of this season's grand classics.
It was enough to send him to the top of the rankings, ahead of Italian Michele Scarponi and fellow Australian Cadel Evans, who won the Tirreno-Adriatico earlier this month.
Germany's Tony Martin, who led the classification after his victory in the Paris-Nice race, completes the top four.
Rankings (after four races):
1. Matthew Goss (AUS) 203 points
2. Michele Scarponi (ITA) 118
3. Cadel Evans (AUS) 108
4. Tony Martin (GER) 108
5. Cameron Meyer (AUS) 106
6. Andreas Klöden (GER) 88
7. Fabian Cancellara (SUI) 86
8. Philippe Gilbert (BEL) 86
9. Ben Swift (GBR) 82
10. Robert Gesink (NED) 80
11. Bradley Wiggins (GBR) 74
12. Vicenzo Nibali (ITA) 71
13. Michael Matthews (AUS) 70
14. Ivan Basso (ITA) 62
15. Alessandro Ballan (ITA) 60
16. Samuel Sanchez (ESP) 59
17. Laurens Ten Dam (NED) 52
18. Filippo Pozzato (ITA) 50
19. Francisco Ventoso (ESP) 46
20. Jean-Christophe Péraud (FRA) 41
