A frustrated Pendlebury was desperate to play after missing the past three matches but the Magpies were not prepared to risk him after doctors took a closer look at the cracked bone in his leg on Thursday.
Defender Chris Tarrant and forward Alan Didak will spend one more week playing for Collingwood's VFL side before again pushing for senior selection.
Tarrant has recovered from a shoulder complaint and Didak has been troubled by an adductor injury.
"Scott won't play this week, he had some extra investigative work done this morning and the doc's decided to give him one more week," Collingwood assistant coach Matthew Lappin told reporters on Thursday.
"We've taken a precautionary approach with Scott and he's training over the weekend to make sure he's right to go next weekend."
Lappin said there was no concern that Pendlebury's tibia injury suffered against Gold Coast on June 3 was worse than expected.
"At the start the doc said six weeks and I think this is six weeks now," Lappin said.
"Nothing's gone wrong or anything, we just decided to give him that extra week to make sure he's 100 per cent right to go and he'll play for us next week."
Pendlebury has been pain free and trained fully for the past four weeks and was bitterly disappointed when told he wouldn't be in the side named on Thursday night.